Table 4.
Endothelial and Pro-Angiogenic Genes Are Up-Regulated in Cav-1−/− MSFs, as Seen by qRT-PCR Analysis
| Gene symbol | Gene name | Fold KO increase | P value |
|---|---|---|---|
| Pecam1 | Platelet/endothelial cell adhesion molecule 1 | 17.5 | 0.020 |
| Tek | TEK Tyrosine Kinase, endothelial | 4.5 | 0.003 |
| Pgf | Placental growth factor | 4.3 | 0.005 |
| Plau | Plasminogen activator, urokinase | 3.8 | 0.04 |
| Il-6 | Interleukin 6 | 3.5 | 0.007 |
| Tbx4 | T Box 4 | 3.0 | 0.005 |
| Tgfb3 | Transforming growth factor, beta 3 | 2.1 | 0.010 |
| Col18a1 | Procollagen, type XVIII, alpha 1 | 2.0 | 0.015 |
| PDGF-A | Platelet derived growth factor, alpha | 1.9 | 0.011 |
| Timp1 | Tissue inhibitor of metalloproteinase 1 | 1.9 | 0.033 |
| Vegf-C | Vascular endothelial growth factor C | 1.6 | 0.001 |