Table 6.

ES Cell Related Genes Up-Regulated in Cav-1^−/− MSFs

ES cell expressed genes (41 genes)

Aurkb, Birc5, Bub1, Bub1b, Cbx5, Ccna2, Ccnb1, Cdc20, Cdc6, Cdca5, Chek1, Dhfr, Dlg7, Dna2l, Ect2, Ercc6l, Fabp5, Fen1, Gmnn, Hells, Hmgb3, Hmmr, Kif2c, Mcm10, Mcm3, Mcm5, Mcm6, Mcm7, Mybl2, Nasp, Npm3, Oip5, Prim1, Prpf40a, Pttg1, Rad51ap1, Rps24, Slc38a1, Slc7a3, Terf1, Wdhd1

Nanog targets (33 genes)

Atad2, Aurka, Bub1b, Cald1, Cbx5, Cdc45l, Cdc7, Cks2, Cyr61, Dlg7, Fanca, H2afx, Hells, Hn1, Kntc1, Lsm5, Nusap1, Oip5, Pbx1, Pcna, Prr11,Rbm39*, Rif1, Rpl17, Set, Slc7a5, Sorbs1, Terf1, Tmem87a, Top2a, Tpx2, Ube2s, Wdhd1

Oct4 targets (11 genes)

Bub1b, Hmgb2, Set, Top2a, Cdc7, Sorbs1, Snx5, Atad2, Hn1, Rif1, Prr11

Sox 2 targets (26 genes)

Atad2, Bub1b, Cbx5, Cdc45l, Cdc7, Crim1, Cth, Cyr61, H2afx, Hells, Hn1, Kif11, Kif2c, Kntc1, Mphosph1, Nusap1, Oip5, Prr11,Rbm39*, Rif1, Set, Sfpq, Slc7a5, Snrpd3, Top2a, Ube2c

Myc targets (36 genes)

Aldh18a1, Cbx5, Ccnb1, Cdc25b, Cdc6, Cks2, Exo1, Fabp5, Fbxo5, Foxm1, H2afx, Hmgn2, Hmmr, Kif11, Kif20a, Mad2l1, Mcm3, Mcm5, Mcm7, Mphosph1, Nxt1, Pabpc1, Pcna, Plk1, Rad51ap1,Rbm39*, Rpl18, Smad7, Snrpd3, Snx5, Spag5, Tagln2, Tgfb3, Tpm2, Trip13, U2af1

ES Cell Common Transcriptional Regulators (8 genes)

Ezh2, Foxm1, Hmgb2, Hmgb3, Mybl2, Trip13, Wdhd1, Whsc1

Note: Underlined genes were up-regulated >5-fold. 

^*Rbm39 = CAPER (Co-Activator of AP-1 and ER).