Lungs from rats infected with Y. pestis CO92 were harvested and perfused with 10% formalin and stained with H&E after 60 minutes (control, A and B), 24 hours (C and D), or 48 hours (E–H) after infection. Boxes in lower magnification images indicate location where the higher magnification images were taken. Original magnifications: ×100 (A, C, E, G); ×400 (B, D, F, H).