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Lung macrophages are recruited to the infection and rapidly killed by Y. pestis. Left lower lobe sections of lungs harvested 1 hour (A and B), 24 hours (C and D), or 48 hours (E and F) after infection were perfused in 10% formalin followed by immunohistochemistry with antibodies to CD68. Images are representative of lesions found in the tissues. Original magnifications: ×100 (A, C, E); ×400 (B, D, F).
