Table 2.
Area under the curve for plasma insulin, glucose, and lactate concentrations with 1-h infusion of A1 receptor antagonist (DPCPX), A2A receptor blocker (ZM-241385), or vehicle in six hypoxic fetal sheep
Insulin | Glucose | Lactate | |
---|---|---|---|
DPCPX | 41.7±2.1 | 98.9±9.5 | 251±24 |
Vehicle | 42.6±3.3 | 123±10 | 253±46 |
P value | 0.69 | 0.15 | 0.98 |
ZM-241385 | 40.3±5.9 | 94.8±15.2 | 256±59 |
Vehicle | 54.6±6.9 | 113±17.5 | 251±38 |
P value | 0.27 | 0.02 | 0.90 |
Area under the curve is presented as concentration ratio·min.