Table 1.
Effects of chronic NOS inhibition on plasma nitric oxide, mean arterial pressure, and tissue blood flow in pigs
n | NOx, μM | MAP, mmHg | Frontal cortex, ml·min−1·100 g−1 | Hypothalamus, ml·min−1·100 g−1 | Pituitary, ml·min−1·100 g−1 | Adrenal, ml·min−1·100 g−1 | |
---|---|---|---|---|---|---|---|
Control | 4 | 12.2±1.9 | 81±5 | 126±17 | 96±4 | 247±67 | 194±26 |
l-NAME | 6 | 6.8±0.7* | 119±8* | 83±9* | 63±5* | 192±26 | 149±10 |
MAP, mean arterial pressure.
P < 0.05 vs. control. NOx, nitric oxide metabolite [n = 19, control; n = 14, N-nitro-l-arginine methyl ester (l-NAME)]. Values are presented as means ± SE.