Table 1.
Means ± SE herpes simplex virus-1 (HSV-1)-immunoreactive cells after injection of the H129 strain of the HSV-1 into IWAT and EWAT
| IWAT (n = 5) | EWAT (n = 4) | |||
|---|---|---|---|---|
| Forebrain | ||||
| Hypothalamic | ||||
| A14 | 2.80±1.96 | 1.00±1.00 | ||
| AH/LA | 15.4±5.80 | 18.00±11.02 | ||
| Arc | 4.2±4.20 | 2.25±1.93 | ||
| DM | 33.2±24.44 | 25.75±14.62 | ||
| DTM | 0.80±0.80 | 0.00 | ||
| LH | 26.20±12.31 | 34.25±22.80 | ||
| Pe/AVPe | 73.60±33.04 | 155.75±86.20 | ||
| PH | 27.80±18.30 | 4.25±3.92 | ||
| POA | 15.00±11.56 | 10.25±7.81 | ||
| PVH | 676.00±199.51 | 736.75±370.59 | ||
| PaAP | 52.80±21.34 | 92.50±67.22 | ||
| PaDC | 35.80±23.61 | 31.00±14.08 | ||
| PaLM | 16.00±6.55 | 40.00±21.15 | ||
| PaMM | 49.40±32.09 | 50.00±34.51 | ||
| PaMP | 222.80±85.67 | 181.50±106.06 | ||
| PaPo | 229.20±59.41 | 183.00±114.64 | ||
| PaV | 70.00±41.29 | 158.75±119.06 | ||
| RCh | 2.20±1.56 | 2.00±2.00 | ||
| SON | 7.00±7.00 | 0.00 | ||
| Spa | 16.20±8.94 | 42.25±27.47 | ||
| SCH | 5.60±3.44 | 5.75±3.33 | ||
| VMH | 3.00±1.84 | 1.00±0.71 | ||
| Thalamic | ||||
| CM | 1.60±0.75 | 0.25±0.25 | ||
| MDM | 2.60±1.47 | 0.00 | ||
| PV | 11.20±5.27 | 5.25±4.92 | ||
| Re/Vre/Xi | 58.60±20.01 | 129.50±81.47 | ||
| Rt | 5.00±2.45 | 8.75±6.37 | ||
| Other forebrain | ||||
| AC | 5.80±5.55 | 1.00±0.71 | ||
| Amygdala/slea | 17.60±17.35 | 7.25±4.57 | ||
| BST | 2.60±1.69 | 2.00±1.68 | ||
| Fascicular | 47.00±27.48 | 32.25±16.62 | ||
| ns | 3.80±2.65 | 3.5±3.50 | ||
| PeF/f | 6.40±2.60 | 22.50±20.23 | ||
| PS | 2.00±2.00 | 0.00 | ||
| SI | 0.00 | 0.50±0.50 | ||
| SubI | 18.40±11.12 | 0.25±0.25 | ||
| Subzi | 6.80±3.97 | 16.50±13.09 | ||
| TC | 3.00±1.41 | 5.33±4.19 | ||
| ZI | 47.00±22.56 | 35.25±17.84 | ||
| Midbrain | ||||
| Collicular | 10.40±4.34 | 2.00±1.22 | ||
| CnF | 4.80±3.57 | 0.00 | ||
| Dk | 2.60±1.44 | 0.25±0.25 | ||
| DpMe | 11.20±3.73 | 9.75±8.17 | ||
| DMTg | 7.40±4.38 | 0.00 | ||
| ERS | 0.80±0.80 | 0.00 | ||
| EW | 0.40±0.40 | 0.25±0.25 | ||
| IF | 0.20±0.20 | 0.50±0.50 | ||
| InC | 2.40±1.75 | 0.50±0.50 | ||
| LDTg | 17.80±8.42 | 12.33±5.51 | ||
| Lemniscus | 20.6±15.99 | 8.25±4.97 | ||
| Mammillary | 0.04±0.04 | 2.00±2.00 | ||
| MiTg | 2.00±1.30 | 0.50±0.29 | ||
| ml/lfp | 18.40±18.40 | 10.25±8.97 | ||
| Oculomotor | 10.20±7.33 | 9.00±6.14 | ||
| Olivary | 119.20±83.99 | 139.00±78.70 | ||
| PAG | 55.60±24.52 | 25.75±15.26 | ||
| Pontine | 62.40±26.41 | 55.50±33.09 | ||
| PPTg | 7.20±4.32 | 6.50±4.09 | ||
| pv | 19.00±8.94 | 28.25±20.03 | ||
| Rubral areas | 119.40±52.21 | 72.00±26.82 | ||
| RtTg/P | 2.60±1.21 | 0.00 | ||
| PN | 1.40±1.40 | 0.00 | ||
| SN | 9.40±5.47 | 10.50±6.16 | ||
| SPTg | 0.00 | 0.00 | ||
| VLTg | 13.60±9.91 | 2.25±2.25 | ||
| VTA | 7.00±5.83 | 0.50±0.50 | ||
| Xscp | 1.40±1.40 | 0.00 | ||
| scp | 7.00±3.59 | 4.50±2.72 | ||
| Brain stem | ||||
| 12/12N | 16.80±8.07 | 14.50±11.14 | ||
| 10 (DMV) | 333.2±122.41 | 807.00±458.47 | ||
| A1/Cl | 267.20±84.02 | 14.00±9.06 | ||
| A2 | 3.00±2.76 | 8.75±8.75 | ||
| A5 | 267.60±51.43 | 106.75±53.98 | ||
| A7 | 4.00±4.00 | 0.00 | ||
| Amb | 102.80±57.54 | 54.00±44.15 | ||
| Abducens | ||||
| 6N | 5.00±5.00 | 0.00 | ||
| Pa6 | 12.00±12.00 | 0.00 | ||
| AP | 35.40±22.31 | 249.50±177.52 | ||
| Bar | 17.20±15.74 | 1.00±1.00 | ||
| CeCv | 10.20±4.63 | 0.00 | ||
| C3 | 21.20±14.94 | 16.75±11.26 | ||
| Cu/Ecu | 26.4±12.30 | 2.75±2.75 | ||
| Facial regions | 324.20±90.71 | 167.75±113.03 | ||
| DPGi | 94.80±43.11 | 42.25±29.01 | ||
| LPGi | 842.4±217.32 | 502.25±246.14 | ||
| Gi | 224.2±97.00 | 167.75±96.73 | ||
| GiA | 144.00±67.05 | 176.75±101.55 | ||
| GiV | 381.80±156.73 | 329.75±210.05 | ||
| KF | 11.60±7.74 | 8.50±8.17 | ||
| LC | 93.8±64.75 | 4.50±2.63 | ||
| Li | 28.8±13.67 | 7.50±5.95 | ||
| Parabrachial areas | ||||
| LPB | 187.80±77.76 | 46.00±30.20 | ||
| MPB | 40.80±29.00 | 10.25±5.15 | ||
| PPy | 9.00±9.00 | 19.00±12.11 | ||
| Pr | 169.20±68.03 | 123.67±73.47 | ||
| Raphe areas | ||||
| DR | 11.20±5.54 | 6.75±5.79 | ||
| RC | 58.80±33.15 | 40.25±29.00 | ||
| RMg | 150.00±37.65 | 137.00±82.01 | ||
| Rob | 195.20±78.53 | 103.50±70.84 | ||
| Rpa | 219.00±79.36 | 243.25±154.78 | ||
| Reticular regions | ||||
| IRt | 1131.40±448.91 | 772.25±538.40 | ||
| LRt | 411.60±132.69 | 247.50±152.79 | ||
| MdD-/V | 224.40±105.37 | 160.50±108.17 | ||
| PCRt | 19.60±8.52 | 11.00±9.41 | ||
| PCRtA | 68.80±28.93 | 56.25±40.58 | ||
| PMn | 122.20±75.84 | 54.75±43.17 | ||
| RVL | 618.20±193.63 | 303.25±160.66 | ||
| Ro | 3.60±2.40 | 3.00±1.91 | ||
| Gr/gr | 11.40±3.06 | 10.75±8.82 | ||
| Sol | 541.60±188.50 | 1010.25±640.78 | ||
| SubCD/V | 261.40±71.59 | 36.00±19.40 | ||
| trigeminal areas | 136.80±59.52 | 63.25±40.26 | ||
| Tz/tz | 12.40±12.15 | 18.50±11.30 | ||
| vestibular areas | 72.40±36.82 | 43.25±28.93 | ||
| vsc | 1777.80±582.86 | 1067.75±596.69 | ||
| X | 2.80±1.71 | 6.25±3.35 | ||
IWAT, inguinal white adipose tissue; EWAT, epididymal white adipose tissue. Forebrain. Hypothalamic: AH, anterior hypothalamus; Arc, arcuate nucleus; DM, dorsomedial nucleus; DTM, dorsal tuberomammillary; LH, lateral hypothalamus; Pe/AVPe, periventricular/anteroperiventricular; PH, posterior hypothalamus; POA, preoptic area; PVH, paraventricular hypothalamus; PaAP, paraventricular hypothalamic anterior, parvicellular; PaDC, parventricular hypothalamic, dorsal cap; PaLM, parventricular hypothalamic, lateral magnocellular; PaMM, paraventricular hypothalamic nucleus, medial magnocellular; PaMP, paraventricular hypothalamic, medial parvocellular; PaPo, paraventricular hypothalamic, posterior; PaV, paraventricular hypothalamic, ventral part; RCh, retrochiasmatic area; SON, supraoptic nucleus; Spa, subparaventricular nucleus; SCH, suprachiasmatic nucleus; VMH, ventromedial hypothalamus. Thalamic: CM, central medial thalamic nucleus; MDM, mediodorsal thalamic nucleus, medial part; PV, parventricular, thalamus; Re/Vre/Xi, reuniens/reuniens, ventral/xiphoid. Other forebrain: AC, anterior commissural nucleus; BST, bed nucleus of the stria terminalis; ns, nigrostriatal bundle; PeF/f, perifornical nucleus/fornix; PS, parastrial nucleus; SI, substantia innominata; SLEA, sublenticular extended amygdala; SubI, subincertal nucleus; subZI, sub zona incerta; TC, Tuber cinerium; ZI, zona incerta. Midbrain. CnF, cuneiform; Dk, darkschewitsch; DMTg, dorsomedial tegmental area; DpMe, deep mesencephalic nucleus; DTg, dorsal tegmental nuclei; ERS, epirubrospinal nucleu; EW, Edinger Westphal; IF, interfascicular nucleus; InC, interstitial nucleus of Cajal; LDTg, laterodorsal tegmental; MiTg, microcellular tegmental nucleus; ml/lfp, medial lemniscus/longitudinal fasciculus of the pons; PAG, periaqueductal gray; PPTg, pedunculopontine nuclei; pv, periventricular fiber system; RtTg/P, reticulotegmental nucleus of the pons/pericentral; PN, paranigral nucleus; SN, substantia nigra; SPTg, subpeduncular tegmental nucleus; VLTg, ventrolateral tegmental nucleus; VTA, ventral tegmental area; xscp, decussation of the superior cerebellar peduncle; scp, superior cerebellar peduncle. Brain stem: 12, hypoglossal nucleus; 10 (DMV), dorsal motor nucleus of the vagus nerve; A1/C1, noradrenaline cells/adrenaline cells; A5, noradrenergic cell field; A7, A7 noradrenaline cells; Amb, ambiguous nucleus; Pa6, paraabducens; AP, area postrema; Bar, Barrington's nucleus; CeCv, central cervical nucleus; C3, adrenergic cell field; Cu/Ecu, cuneate/external cuneate; DPGi, dorsal paragigantocellular nucleus; Gi-A/V, gigantocellular reticular nucleus-alpha/ventral; KF, Kolliker-Fuse nucleus; LC, locus coeruleus; Li, linear nucleus of the medulla; LPGi, lateral paragigantocellular nucleus; LPB, lateral parabrachial nucleus; MPB, medial parabrachial nucleus; PPy, peripyramidal nucleus; Pr, prepositus hypoglossal nucleus; DR, dorsal raphe; RC, raphe cap; RMg, raphe magnus nucleus; Rob, raphe obscurus; Rpa, raphe pallidus; Irt, intermediate reticular nucleus; LRt, lateral reticular nucleus; MdD-/V, medullary nucleus dorsal-/ventral; PCRt-/A, parvicellular reticular nucleus; PMn, paramedian reticular nucleus; RVL, rostroventrolateral reticular nucleus; Ro, nucleus of Roller; Gr/gr, gracile nucleus/fasciculus; Sol, solitary tract nucleus; SubCD/-V, subcoeruleus nucleus, dorsal/-ventral; Tz/tz, trapezoid nucleus/body; vsc, ventral spinocerebellar tract; X, nucleus X.