Table 4.

Summary of the Performance of ER Classification

	Discovery (n = 67)		Validation (n = 333)
	ΔΔCT cutoff-point	Clustering	ΔΔCT cutoff-point	Clustering
Sensitivity	0.96 (0.86−1.00)	0.96 (0.86−1.00)	0.99 (0.97−1.00)	0.96 (0.94−0.98)
Specificity	0.88 (0.64−0.99)	1.00 (0.80−1.00)	0.95 (0.74−1.00)	1.00 (0.82−1.00)
PPV	0.96 (0.86−1.00)	1.00 (0.93−1.00)	1.00 (0.98−1.00)	1.00 (0.99−1.00)
NPV	0.88 (0.64−0.99)	0.89 (0.67−0.99)	0.82 (0.60−0.95)	0.63 (0.44−0.80)
Accuracy	0.94 (0.85−0.98)	0.97 (0.90−1.00)	0.98 (0.97−1.00)	0.97 (0.94−0.98)
Kappa	0.842 (0.693−0.992)	0.924 (0.821−1.000)	0.870 (0.758−0.982)	0.759 (0.623−0.895)