Table 6.

Summary of the Performance of PR Classification

	Discovery (n = 67)		Validation (n = 321)
	ΔΔCT cutoff-point	Clustering	ΔΔCT cutoff-point	Clustering
Sensitivity	0.94 (0.82−0.99)	0.87 (0.74−0.95)	0.95 (0.92−0.97)	0.93 (0.89−0.96)
Specificity	0.95 (0.75−1.00)	0.95 (0.75−1.00)	0.73 (0.57−0.85)	0.82 (0.67−0.92)
PPV	0.98 (0.88−1.00)	0.98 (0.87−1.00)	0.96 (0.93−0.98)	0.97 (0.94−0.99)
NPV	0.86 (0.65−0.97)	0.76 (0.55−0.91)	0.70 (0.54−0.82)	0.64 (0.50−0.77)
Accuracy	0.94 (0.85−0.98)	0.90 (0.80−0.96)	0.92 (0.88−0.95)	0.91 (0.88−0.94)
Kappa	0.861 (0.730−0.993)	0.767 (0.607−0.928)	0.664 (0.544−0.784)	0.669 (0.556−0.782)