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. Author manuscript; available in PMC: 2010 Jan 19.
Published in final edited form as: Chem Res Toxicol. 2009 Jan;22(1):218–226. doi: 10.1021/tx8003714

Figure 6.

Figure 6

Morphology of sciatic nerve cross-sections stained with toluidine blue. (A) Cross section obtained from a control rat showing the presence of large and small myelinated axons. The axons (a) are surrounded by normal compact myelin. A Schwann cell has been sectioned through its cytoplasm (*). (B) Cross section of a nerve obtained from a SADC-exposed rat showing normal large and small myelinated axons. (C) Cross section of a sciatic nerve from an animal exposed to DEDC for 8 weeks demonstrating an axon with intramyelinic edema (blue arrow), a demyelinated axon (red arrow) surrounded by Schwann cell cytoplasm, and degenerating axon (yellow arrow).