Table 1.
WBC | RBC | MCV | HBG | HCT | MCH | MCHC | RDW | PLT | % Retic | |
---|---|---|---|---|---|---|---|---|---|---|
Wild-type | 7.6 (± 1.8) | 10.8 (± 0.7) | 45.5 (± 1.5) | 16.1 (± 3.4) | 49.1 (± 3.4) | 14.9 (± 3.0) | 32.8 (± 6.6) | 14.5 (± 1.6) | 1075 (± 144.3) | 2.5 (± 0.9) |
RBC2/+ | 7.49 (± 2.3) | 11.64 (± 1.0) | 41.0 (± 1.1) | 15.6 (± 3.1) | 46.4 (± 4.95) | 13.7 (± 1.6) | 33.4 (± 3.9) | 17.1 (± 6.7) | 1080 (± 211) | 3.0 (± 1.1) |
RBC2/RBC2 | 214.15 (± 30.8) | 5.55 (± 0.93) | 48.52 (± 5.48) | 6.73 (± 0.90) | 26.61 (± 3.64) | 12.25 (± 0.89) | 25.4 (± 2.27) | 37.94 (± 2.71) | 1716 (± 591) | 30.5 (± 6.8) |
Automated full blood counts were obtained on 40 wild-type and RBC2/+ mice, and 15 RBC2/RBC2 mice at 5 weeks of age. Values are presented plus or minus the standard deviation. Student t-tests were performed. Comparison of RBC2/+ with wild-type showed all blood parameters had P values greater than .05 except for the MCV, HCT, and RDW, which were all less than .05. Comparison of RBC2/RBC2 with wild-type showed P values less than .05 for all parameters measured. P values less than .05 were considered significant.
WBC indicates white blood cell count; RBC, red blood cell count; MCV, mean corpuscular volume; HBG, hemoglobin; HCT, hematocrit; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; RDW, red cell distribution width; PLT, platelet count; and % Retic, % reticulocytes.