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. Author manuscript; available in PMC: 2009 Apr 6.
Published in final edited form as: J Cardiovasc Pharmacol. 2008 Apr;51(4):418–423. doi: 10.1097/FJC.0b013e318168400a

Table 2.

Perioperative Chemistry and Hematology Values in Patients Receiving Aprotinin or EACA During Cardiac Surgery

Variable Aprotinin
(n=30)
EACA
(n=30)
Sodium (mmol/L) Baseline 143.1±1.5 139.2±0.9
Post 16.27±3.3* 161.5±4.7*
Potassium (mmol/L) Baseline 5.63±0.17 5.25±0.13
Post 5.79+0.15 5.53±0.26
Chloride (mmol/L) Baseline 110.4±1.2 107.4±0.9
Post 127.4±2.6* 126.5±3.7*
Blood Urea Nitrogen
(mg/dL)
Baseline 13.6±1.0 16.6±2.7
Post 16.3±1.1 18.2±2.2
Creatinine (mg/dL) Baseline 0.9±0.0 1.2±0.2
Post 1.1±0.0 1.5±0.2
Hemaglobin (g/dL) Baseline 12.8±0.3 12.0±0.3
Post 11.2±0.3* 10.5±0.2*
Hematocrit (%) Baseline 37.0±0.9 35.0±0.9
Post 32.4±0.7* 30.8±0.6*
Platelet Density (×10−3) Baseline 196±10 202±11
Post 148±7* 141±7*

EACA: epsilon-aminocaproic acid

Post: 6 hours post operatively

All values reported as MEAN±SEM

*

p<0.05 vs. Baseline