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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Am J Kidney Dis. 2008 Dec 19;53(3):426–437. doi: 10.1053/j.ajkd.2008.09.024

Table 4.

Associations between eGFR Effect (per 10 ml/min/1.73m2 increase) and 4 Guideline-recommended Discharge Therapies According to Hospital Performance Groups

Category Adjusted OR (95% CI)a P-value
Discharge Aspirin 0.02b
 eGFR effect in leading (>75%) hospitals 1.06 (1.02, 1.11) 0.003
 eGFR effect in 50–75% hospitals 1.05 (1.02, 1.08) 0.002
 eGFR effect in 25–50% hospitals 1.06 (1.03, 1.09) <0.001
 eGFR effect in lagging (≤25%) hospitals 1.00 (0.98, 1.02) 0.9
Discharge clopidogrel 0.02b
 eGFR effect in leading (>75%) hospitals 1.03 (1.01, 1.048) 0.002
 eGFR effect in 50–75% hospitals 1.04 (1.03, 1.058) <0.001
 eGFR effect in 25–50% hospitals 1.02 (1.00, 1.03) 0.08
 eGFR effect in lagging (≤25%) hospitals 0.99 (0.97, 1.02) 0.5
Discharge lipid-lowering agentc 0.01b
 eGFR effect in leading (>75%) hospitals 1.050 (1.02, 1.08) <0.001
 eGFR effect in 50–75% hospitals 1.051 (1.02, 1.08) 0.001
 eGFR effect in 25–50% hospitals 1.04 (1.01, 1.07) 0.007
 eGFR effect in lagging (≤25%) hospitals 1.00 (0.96, 1.03) 0.8
Discharge ACE inhibitorsd 0.05b
 eGFR effect in leading (>75%) hospitals 1.02 (0.99, 1.04) 0.2
 eGFR effect in 50–75% hospitals 1.04 (1.01, 1.07) 0.02
 eGFR effect in 25–50% hospitals 1.00 (0.98, 1.03) 0.9
 eGFR effect in lagging (≤25%) hospitals 1.05 (1.03, 1.07) <0.001

Abbreviations: eGFR, estimated glomerular filtration rate; ACE, angiotensin-converting enzyme.

a

Variables in the model – sex, white race, body mass index, age, heart rate, systolic blood pressure, family history of coronary artery disease, hypertension, diabetes, current/recent smoker, dyslipidemia, prior myocardial infarction, prior percutaneous coronary intervention, prior coronary artery bypass surgery, prior heart failure, prior stroke, ischemic electrocardiogram abnormalities, heart failure, positive cardiac markers; primary attending, insurance type, number of hospital beds, region, hospital capabilities, teaching/nonteaching hospital.

b

P-value for comparison of Odds Ratios between leading and lagging hospital rank groups

c

Among patients with history of dyslipidemia or low-density lipoprotein cholesterol levels >100 mg/dL

d

Among patients with history of, signs of, or in-hospital congestive heart failure, ejection fraction <40%, severe or moderate left ventricle dysfunction, diabetes mellitus, or hypertension