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Correlation of Rho kinase inhibition with fasudil and change in endothelium-dependent vasodilation. For the entire cohort of 28 patients, the change in flow-mediated, endothelium-dependent vasodilation after fasudil relative to placebo was inversely proportional to the extent of Rho kinase inhibition with fasudil (r=−0.48, P=0.01). Squares represent CAD and triangles represent healthy subjects, respectively.
