Table 2.

Overall per allele median ORs and 95% probability intervals (PIs) for the association between two SNPs in the TP53 region and invasive ovarian cancer in non-Hispanic whites, by histologic subtype, adjusted for age and study site^*+

Polymorphism	Histology	N cases	N controls	Posterior Median OR	(95% Probability Intervals)	Bayes Factor	P(OR >1 | Data)
rs2287498†	Serous	1,859	5,927	1.30	(1.07 – 1.57)	165.7	0.99
	Mucinous	301	5,927	1.07	(0.74 – 1.54)	1.8	0.64
	Endometrioid	555	5,927	1.25	(0.94 - 1.65)	14.0	0.93
	Clear Cell	288	5,927	0.95	(0.62 – 1.39)	0.7	0.41
rs12951053‡	Serous	2,585	8,508	1.19	(1.01 – 1.38)	47.8	0.98
	Mucinous	354	8,508	1.06	(0.76 – 1.43)	1.8	0.64
	Endometrioid	782	8,508	1.31	(1.05 – 1.62)	109.6	0.99
	Clear Cell	410	8,508	1.00	(0.73– 1.34)	1.0	0.50

^*Results in bold type have probability intervals that excludes 1.0

^†Includes the following OCAC sites: HAW, MALOVA, MAYO, NCOCS, POCS, SEA, STA, UKO, USC

^‡Includes the following OCAC sites: AUS, HAW, MALOVA, MAYO, NCOCS, NEC, NHS, POCS, SEA, STA, UCI, UKO, USC

⁺Analyses are adjusted for age and prior breast cancer