TABLE 1.
Effect of selective HDL delipidation on plasma lipids, apolipoproteins, and LCAT and cholestryl ester transfer protein (CETP) of human plasma
| Pretreatment (SD) | Posttreatment (SD) | P value | |
|---|---|---|---|
| Total cholesterol | 159 (24) | 141 (22) | <0.0002 |
| Unesterified cholesterol | 41 (7) | 37 (8) | <0.001 |
| Total triglyceride | 164 (121) | 141 (108) | 0.3 |
| Total phospholipid | 186 (26) | 158 (27) | <0.0001 |
| HDL-cholesterol | 42 (9) | 10 (6) | <0.0001 |
| LDL-cholesterol | 95 (21) | 98 (20) | 0.598 |
| VLDL-cholesterol | 22 (16) | 34 (17) | <0.0003 |
| ApoA-I | 109 (14) | 81 (15) | <0.0001 |
| ApoB | 72 (14) | 66 (13) | <0.03 |
| LCATa | 7.4 (3.0) | 7.9 (3.0) | 0.42 |
| CETPa | 518 (182) | 131 (35) | <0.003 |
N = 51. Units = (mg/dl) except LCAT (μg/ml/h) and CETP (nmol/ml/h).
a
N = 6.