Table 2.
Genotypes detected for the SNPs at positions −660, −528 and −524 in the 5′ flanking region of the HSP90AA1 gene
Genotype LYF SIF SP1a | Number of animals | Number of healthy animals | Number of infected animals | Probability of healthy animals | Probability of infected animals |
---|---|---|---|---|---|
CC AA GGb | 2 | 2 | 0 | 0.050 | 0.000 |
CC AA GT | 11 | 10 | 1 | 0.250 | 0.037 |
CC AA TT | 27 | 19 | 8 | 0.475 | 0.296 |
CG AA TTb | 1 | 0 | 1 | 0.000 | 0.037 |
CG AG GTb | 5 | 1 | 4 | 0.025 | 0.149 |
CG AG TT | 18 | 7 | 11 | 0.175 | 0.407 |
GG GG TTb | 3 | 1 | 2 | 0.025 | 0.074 |
67 | 40 | 27 |
The number of healthy and infected Rasa Aragonesa breed sheep and the probability of developing the disease based on the genotype are shown. χ2 = 15.9452 for the contingency table and p value = 0.014 (p < 0.05)
aPutative regulatory motif that could be affected by the SNP
bThe estimated probabilities for these genotypes should be cautiously considered due to the small number of animals found in the analyzed sample.