Table 3.
Overall survival (OS): Patient and tumor characteristics and prognostic factors in the entire population of grade III oligodendrogliomas
| Median OS (years) | Univariate Analysis
|
Multivariate Analysis
|
||||||
|---|---|---|---|---|---|---|---|---|
| Characteristics | n | % | p-Value | HR (95%CI) | p-Value | RR (95% CI) | ||
| Age | ⩽50.3 years | 26 | 50 | 2.5 | ||||
| >50.3 years | 26 | 50 | 1.9 | NS | 0.72 (0.31–1.55) | |||
| Gender | Men | 26 | 50 | 2.2 | ||||
| Women | 26 | 50 | 2.2 | NS | 0.83 (0.37–1.79) | |||
| Extent of surgery | Resection | 35 | 67 | 3.5 | ||||
| Biopsy | 17 | 33 | 1.7 | p < 0.05 | 0.47 (0.13–0.99) | NS | ||
| KPS | ⩾90 | 26 | 53 | 3.5 | ||||
| < 90 | 23 | 47 | 2 | p < 0.05 | 0.47 (0.19–1.00) | NS | ||
| Gene amplification | 0 | 38 | 73 | 2.8 | ||||
| ⩾1 | 14 | 27 | 1.6 | p = 0.05 | 2.07 (0.99–6.48) | p = 0.03 | 2.5 (1.1–5.7) | |
| Chromosomes 1p/19q status | Codeleted | 15 | 29 | 6.7 | ||||
| Not codeleted | 37 | 71 | 1.9 | p < 0.05 | 0.32 (0.17–0.99) | NS | ||
Abbreviations: HR, hazard ratio; CI, confidence interval; RR, relative risk; NS, not significant.