Table 2.
Characteristics of historical controls versus patients in current protocol
| Characteristic | Historical Group | Current Protocol | p-Value |
|---|---|---|---|
| Number of patients | 14 | 23 | |
| Mean age at diagnosis ± SD (years) | 6.3 ± 2.7 | 9.2 ± 4.9 | 0.056 |
| Male/female ratio | 4/10 | 10/13 | |
| Mean duration of symptoms ± SD (days) | 39.4 ± 24.5 | 63.9 ± 58.4 | 0.48 |
| Surgery | |||
| Biopsy ± debulking | 2 | 4 | |
| Primary shunt | 1 | 1 | |
| Secondary shunt | 2 | 6 | |
| Secondary surgery | 1 | 0 | |
| None | 8 | 12 | |
| Steroid withdrawala | 7/14 (50%) | 12/22 (55%) | 0.79 |
| Total stay in hospital ± SD (days) | 24.9 ± 22.0 | 57.3 ± 21.8 | 0.001 |
a
Data missing for one patient.