Table 3.

Diagnosis findings and outcome in experimental cohort

Patient	Age (Years)	Sex	Delay Symptoms/Diagnosis (Days)	% Invasion	Surgery	Chemotherapy before RT (Number of Courses)	Steroid Withdrawn	Delay, Diagnosis to RT (Days)	RT Dose (Gy)	Delay, Diagnosis to Death (Months)	Cause of Death
1	8	F	42	90	No	4 GRT + 5 MTX	Y	248	54	15	DOD
2	5	F	94	100	Shunt II	2 GRT	Y	35	54	20	DOD
3	7	F	16	90	No	4 GRT + 1 MTX	N		0	8	DOD
4	4	F	27	75	Biopsy	4 GRT + 7 MTX	Y	344	54	22	DOD
5	12	M	108	75	Biopsy	1 GRT	Y	58	54	35	DOD
6	16	F	112	75	No	3 GR + 6 MTX	N	256	54	13	DOD
7	7	F	11	75	Biopsy	4 GR + 8 MTX	Y	318	54	18	DOD
8	14	M	66	90	Ventriculo II	4 GR + 6 MTX	Y	296	54	27	DOD
9	7	F	50	75	Shunt II	2 GR + 4 MTX	N	190	54	11	DOD
10	7	M	59	75	Shunt II	3 GR + 6 MTX	N	293	54	17	DOD
11	4	M	15	90	Shunt I	4 GR + 8 MTX	Y	351	54	21	DOD
12	15	F	95	75	Shunt II	4 GR + 7 MTX	N	376	54	20	DOD
13	9	F	96	50	No	4 GR + 8 MTX	Y	372	54	26	DOD
14	13	F	8		No	1 GR + 2 MTX	N	103	54	6	DTOX
15	17	M	184	50	Biopsy	2 GR + 4 MTX	N	206	6	7	DOD
16	20	M	211	75	No	3 GR + 6 MTX	Y	778	54	73	DOD
17	8	M	137	75	No	2 GR + 4 MTX	N	215	30	13	DOD
18	10	F	11		Shunt II	3 GR + 5 MTX	Y		0	9	DOD
19	10	F	9	75	No	4 GR + 6 MTX	N	296	28	11	DOD
20	3	M	16	100	No	4 GR + 8 MTX	Y	377	54	26	DOD
21	6	F	2	75	No	4 GR + 2 MTX	Y	227	54	10	DOD
22	4	M	22	75	No	3 GR + 2 MTX	N	147	42	8	DOD
23	4	M	55	100	No	1 GR + 2 MTX	N	98	45	15	DOD

Abbreviations: RT, radiotherapy; F, Female; II, performed after diagnosis; GRT, Grossman-tamoxifen; MTX, high-dose methotrexate; Y, yes; M, male; DOD, dead of disease; N, no; GR, Grossman; Ventriculo, ventriculocisternostomy; I, performed at diagnosis; DTOX, dead of toxicity.