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Baseline demographic and clinical characteristics
| Characteristic | n (%) or Median (Range) |
|---|---|
| Age (years) | 52 (25 – 70) |
| Gender, male | 16 (64) |
| KPS | |
| 60% | 1 (4) |
| 70% or 80% | 11 (44) |
| 90% or 100% | 13 (52) |
| Histological diagnosis | |
| Glioblastoma multiforme | 22 (88) |
| Anaplastic astrocytoma | 2 (8) |
| Anaplastic oligodendroglioma | 1 (4) |
| Prior chemotherapy regimens | |
| 0 | 1 (4) |
| 1 | 24 (96) |
| Concomitant antiseizure drugs | |
| Enzyme inducing | 13 (52) |
| None or not enzyme inducing | 12 (48) |
