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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Europace. 2008 May 30;10(7):868–876. doi: 10.1093/europace/eun138

Figure 2.

Figure 2

Adrenergic response modulates guinea pig M cell action potential. At 1000 ms basic cycle length, isoproterenol (1 μM) shortens APD (A). (B) Action potential duration measured at 90% repolarization (APD90) under different BCLs: 300, 500, 800, 1000, and 2000 ms. Isoproterenol significantly decreased APD90 at 800 and 1000 ms. Phase 0 amplitude (APA) shows significant increment in the presence of isoproterenol (1 μM), under different BCLs (C). Values are mean ± SEM, n = 4. *P < 0.05 and **P < 0.005.