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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Europace. 2008 May 30;10(7):868–876. doi: 10.1093/europace/eun138

Table 1.

Action potential results

(ms) 300 500 800 1000 2000
RMP (-mV)
 Control 79.2 ± 3.7 80.3 ± 3.3 80.3 ± 3.2 79.3 ± 3.2 79.4 ± 3.1
 Ab-β (n = 7) 80.8 ± 3.9 81.1 ± 3.7 80.7 ± 3.6 80.2 ± 3.3 79.1 ± 3.1
Phase 0 amplitude (mV)
 Control 121.6 ± 1.5 122.5 ± 1.6 123.6 ± 1.3 124.0 ± 1.4 124.8 ± 1.5
 Ab-β 120.1 ± 3.5 122.3 ± 2.7 123.0 ± 2.5 123.0 ± 2.6 123.2 ± 2.9
APD90 (ms)
 Control 148.8 ± 3.8* 166.1 ± 4.2 176.0 ± 3.5 179.4 ± 2.5* 178.7 ± 3.9
 Ab-β 135.1 ± 3.1* 162.6 ± 4.7 167.9 ± 2.8 170.3 ± 2.2* 173.5 ± 1.6
APD30 (ms)
 Control 64.2 ± 4.9 76.2 ± 4.9 82.1 ± 3.4 89.1 ± 3.1 92.7 ± 3.1
 Ab-β 56.9 ± 4.2 71.5 ± 3.5 82.5 ± 1.9 84.1 ± 3.2 90.6 ± 2.3
RMP (-mV)
 Control 86.3 ± 2.9 86.1 ± 3.0 86.1 ± 3.2 85.1 ± 3.2 83.4 ± 3.1
 Ab- (n = 8) 85.3 ± 2.7 84.9 ± 2.8 85.0 ± 3.0 84.5 ± 2.8 85.2 ± 2.9
Phase 0 amplitude (mV)
 Control 121.1 ± 1.8 122.3 ± 1.7 123.4 ± 1.6 123.2 ± 1.7 124.6 ± 1.9
 Ab- 121.3 ± 2.6 123.5 ± 2.5 124.7 ± 2.5 125.3 ± 2.6 126.5 ± 2.2
APD90 (ms)
 Control 136.7 ± 6.7 153.6 ± 6.8 162.3 ± 6.8 167.5 ± 7.8 166.1 ± 7.2
 Ab- 133.5 ± 7.2 152.0 ± 7.5 159.6 ± 8.3 162.8 ± 8.3 160.2 ± 8.0
APD30 (ms)
 Control 63.9 ± 2.6 72.8 ± 3.6 85.7 ± 3.2 90.7 ± 3.9 92.9 ± 3.7
 Ab- 58.3 ± 3.9 70.7 ± 4.6 79.7 ± 3.7 85.5 ± 3.4 90.1 ± 3.2

BCL, basic cycle lengths; RMP, resting membrane potential; APD90, action potential duration at 90% repolarization; APD30, action potential duration at 30% repolarization;

*

P < 0.05, control vs. Ab-β. All values are expressed as mean ± SEM.