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. Author manuscript; available in PMC: 2009 Apr 7.
Published in final edited form as: Clin Infect Dis. 2009 Feb 1;48(3):274–284. doi: 10.1086/595844

Table. 1.

Estimates and values for the transmission dynamics of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) and hospital-acquired MRSA (HA-MRSA).

Variable Symbol Baseline value Source
Total no. of patients N 400
No. of admissions per day
 Total Λ 70 BI
 Patients colonized with CA-MRSA λCC 0.03 [19, 20 ]
 Patients colonized with HA-MRSA λCH 0.07 BI, [19, 20 ]
 Patients infected with CA-MRSA λIC 0.005 [11]
 Patients infected with HA-MRSA λIH 0.0017 [11]
Length of stay, by patient group
 Susceptible patients γS=1/5 5 days BI
 Patients colonized with CA-MRSA γCC=1/5 5 days BI
 Patients colonized with HA-MRSA γHC=1/7 7 days [14]
 Patients infected with CA-MRSA γIC=1/10 10 days [14]
 Patients infected with HA-MRSA γIH=1/18 18 days [14]
Hand hygiene compliance efficacy, % η 60 [21]
Transmission rate per susceptible patienta
 Patients colonized with CA-MRSA
  per patient colonized with CA-MRSA/N
βCC 0.36 per day [22, 23]
 Patients colonized with HA-MRSA per
  patient colonized with HA-MRSA/N
βCH 0.27 per day [22, 23]
 Patients colonized with CA-MRSA per
  patient infected with CA-MRSA/N
βIC 0.09 per day [22, 23]
 Patients colonized with HA-MRSA per
  patient infected with HA-MRSA/N
βIH 0.07 per day [22, 23]
Rate of infection per colonized patient per
 day of length of stay, %
 CA-MRSA 100 ϕC 10 γCC [24]
 HA-MRSA 100 ϕH 10 γCH [24]
Death rate per infected patient per day of
 length of stay, %
 CA-MRSA 100 δC 3.3 γIC [1, 25]
 HA-MRSA 100 δH 20.0 γIH [1, 25]
Infection cure rate per infected patient per
 day of length of stay, %
 CA-MRSA 100 τC 96.7 γIC [1, 25]
 HA-MRSA 100 τH 80.0 γIH [1, 25]
Decolonization rate per colonized patient
 per day of length of stay, %
 CA-MRSA 100 αC 0 γCC [26, 27]
 HA-MRSA 100 αH 0 γCH

NOTE. BI, data obtained from the Beth Israel Deaconess Medical Center.

a

Transmission of MRSA from a colonized or infected patient to a susceptible patient with an assumption that hand hygiene compliance is 0%.