Table 3.

Associations of COX-2 Diplotypes with OPL Risk

Diplotype	Controls (%)	Cases (%)	Adjusted OR (95% CI)*	P
Overall
WWW / WWW	49 (34.27)	69 (52.27)	1.00 (ref.)
WWW / WMW	33 (23.08)	26 (19.70)	0.44 (0.22−0.89)	0.022
WWW / MMW	34 (23.78)	23 (17.42)	0.51 (0.26−1.02)	0.055
WMW / WMW	6 (4.20)	2 (1.52)	0.29 (0.50−1.62)	0.157
WMW / MMW	8 (5.59)	7 (5.30)	0.63 (0.20−2.00)	0.429

OR indicates odds ratio; CI, confidence interval; W, wild-type allele; WW, homozygous wild-type genotype; WM, heterozygous genotype; M, variant allele; MM, homozygous variant genotype.

^*Adjusted for age, gender, ethnicity, smoking status, and alcohol consumption.