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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Cancer. 2009 Apr 1;115(7):1498–1506. doi: 10.1002/cncr.24157

Table 3.

Associations of COX-2 Diplotypes with OPL Risk

Diplotype Controls (%) Cases (%) Adjusted OR (95% CI)* P
Overall
WWW / WWW 49 (34.27) 69 (52.27) 1.00 (ref.)
WWW / WMW 33 (23.08) 26 (19.70) 0.44 (0.22−0.89) 0.022
WWW / MMW 34 (23.78) 23 (17.42) 0.51 (0.26−1.02) 0.055
WMW / WMW 6 (4.20) 2 (1.52) 0.29 (0.50−1.62) 0.157
WMW / MMW 8 (5.59) 7 (5.30) 0.63 (0.20−2.00) 0.429

OR indicates odds ratio; CI, confidence interval; W, wild-type allele; WW, homozygous wild-type genotype; WM, heterozygous genotype; M, variant allele; MM, homozygous variant genotype.

*

Adjusted for age, gender, ethnicity, smoking status, and alcohol consumption.