Fig. 2.
Structure of IL-23. (a) Side view of the IL-23 crystal structure. p19 helices A to D are colored in magenta, and p40 domains 1 to 3 colored in blue. The single N-acetylglucosamine residue attached to Asn200 on p40 is shown in red. Disulfide linkages are colored in yellow. (b) Face-on view of IL-23. Receptor interaction sites 2 and 3 are highlighted in ovals, and the key site 3-interacting sidechain of Trp137 is displayed.
