Table I.
Details of infection with Bovine viral diarrhea virus (BVDV), vaccination against several bovine viruses, and antibody responses in persistently infected (PI) cattle commingled for 11 mo
| BVDV antibody; titerb on day 0/day 342 of commingling
|
||||||
|---|---|---|---|---|---|---|
| Dates of vaccination and initial diagnosis (2005) | Animal no. | BVDV subtype | Vaccine typea | 1a | 1b | 2a |
| 8/26, 8/26 | 8232c | 2a | MLV | 128 | 32 | 512 |
| 7/25, 9/14 | 8233 | 2a | MLV | 4/256 | 4/128 | 0/0 |
| 5/30, 7/30 | 8234 | 1b | MLV | 0/0 | 0/0 | 0/0 |
| 7/25, 9/20 | 8235 | 1a | Killed | 0/128 | 0/8 | 0/64 |
| 10/4, 10/3 | 8236 | 1a | MLV | 2048/2048 | 512/128 | 1024/512 |
| 5/25, 7/25 | 8237 | 1b | Killed | 0/16 | 0/4 | 0/64 |
| 10/17, 10/17 | 8238 | 1b | MLV | 1024/256 | 4/0 | 256/64 |
| 8/18, 8/18 | 8239 | 1b | MLV | 2048/1024 | 128/128 | 256/64 |
| 10/4, 10/3 | 8240 | 1a | MLV | 1024/256 | 32/32 | 256/32 |
| 9/22, 9/22 | 8241 | 1a | MLV | 1024/512 | 4/4 | 64/8 |
| 8/26, 8/26 | 8242c | 2a | MLV | 512 | 32 | 64 |
| 10/11, 9/19 | 8243c | 2a | MLV | 0 | 0 | 0 |
MLV — modified live virus.
a
The vaccine contained MLV or killed BVDV-1a Singer and BVDV-2a 5912, among other components.
b
Reciprocal of the end-point titer in the viral neutralization test (VNT) in the day 0 and day 342 collections; zero indicates a titer of < 1:4.
c
Died with mucosal signs and lesions on May 6 (study day 137), April 18 (day 119), and January 2 (day 13), 2006, respectively.