Figure 4.—

Age-dependent NDJ in ord⁸/ord¹⁰ oocytes. Each bar denotes the percentage of X chromosome NDJ in aged (shaded) or nonaged (open) oocytes. Error bars represent 95% confidence intervals. In ord⁸/ord¹⁰ oocytes, normal X chromosomes exhibit age-dependent NDJ in all three broods tested (•••P = 0.0004, ••P = 0.0001, •P = 0.0002; N > 1900 for each brood). The raw data is presented in supplemental Table S3. These data contrast sharply with those observed for ord⁴/ord¹⁰ oocytes (see supplemental Figure S1A).