TABLE 2.
Positions
|
||||||||
---|---|---|---|---|---|---|---|---|
Consensusa | −4 | −3 | −2 | −1 | AUG | +4 | +5 | +6 |
Balance (1986) | C | A | C/A | A/C | AUG | G/U | C | |
Hamilton et al. (1987) | A/C | A | A | A/C | AUG | U | C | U/C |
Kozak (1986, 1997) | C | A/G | C | C | AUG | G | ||
Arst and Sheerins (1996) | G | X | X | AUG | C/U | C | ||
Positions
|
||||||||
Flanking sequencesb | −4 | −3 | −2 | −1 | AUG | +4 | +5 | +6 |
AUG of uaY12 uORFA | C | A | U | U | AUG | G | G | U |
AUG of uaY ORF | C | G | U | U | AUG | C | U | G |
uAUG 3 in −44 of uaY | A | G | A | C | AUG | G | U | G |
uAUG 2 in −122 of uaY | C | U | A | C | AUG | C | G | U |
uAUG 1 in −338 of uaY | A | G | U | C | AUG | C | G | C |
Consensus sequences flanking the AUG start codon according to different references in the literature.
Sequences flanking the AUG codon of the uaY ORF and of the new uaY12 aberrant AUG (uORFA), together with the three natural AUGs, which are found in the wild-type uaY 5′-UTR at positions −338, −122, and −44.