TABLE 3.
Chromosomal location | Fold change (± SD)
|
||
---|---|---|---|
Reporter | dSETDB1KD | Su(var)3-906/+ | |
118E-28 | X, pericentric | 7.8 ± 0.9 | 3.7 ± 0.1 |
39C-2 | 2L, pericentric | 6.6 ± 0.7 | 2.3 ± 0.5 |
118E-10 | 4, pericentric | 7.5 ± 1.0 | 2.0 ± 0.2 |
39C-12 | 4, arm | 8.6 ± 0.8 | −2.6 ± 0.1 |
118E-25-5 | 4, arm | 9.7 ± 0.2 | −2.3 ± 0.1 |
PEV modification by HMT mutations. Fold change in pigmentation in dominant modification assays upon knockdown of dSETDB1 expression (5–25% transcript quantities relative to wild type; dSETDB1hp2101B driven by daGAL4) or with the Su(var)3-906 allele (dominant effect). Mean fold change from the parental pigmentation is indicated with standard deviation from the mean; negative values indicate fold enhancement of PEV.