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Cross-species complementation of SIR1 paralogs in S. bayanus and S. cerevisiae. (A) S. cerevisiae sir1 yeast contain the reporter hmr∷TRP1 or hmlα2∷ADE2, complemented by S. bayanus SIR1 paralogs expressed from pRS316 plasmids. (B) Patch mating tests of MATa S. bayanus sir1 or kos mutants carrying a plasmid with S. cerevisiae SIR1.
