TABLE 2.

Binding constants from NMR titrations

Shown are the weak and upper limit to the tight binding constants for the CR2-C3d and CR2-C3dp1 interactions. The binding constants were calculated using NMR titrations, monitoring chemical shift changes. The binding curves are found in Fig. 4, B and D. UL, upper limit.

Ligand/Peptide	Binding mode	Kd
		μm
C3d	Tight, UL	45
	Weak	130 ± 60
C3dp1	Tight, UL	45
	Weak	500 ± 250