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Comparisons based on space similarity. a) Hess metric applied using as many singular vectors as members in the superfamily. The x-axis is sorted by increasing number of members in the superfamily (the name of the reference member is written). b) Z-score of the Hess metric for a random model (See Methods for details). c) Z-score* of the Hess metric for a pseudo-random model (See Methods for details).
