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. 2000 Jan 4;97(1):360–364. doi: 10.1073/pnas.97.1.360

Figure 3.

Figure 3

(A) Annexin V (10 μmol/liter) significantly reduced the binding of platelets to BLOX-1-CHO (P < 0.01). (B) Thrombin (1 unit/ml) stimulation enhanced the binding of platelets to BLOX-1-CHO. The fluorescence of the cells that were not incubated with platelets is indicated by a broken line. (C) Thrombin dose-dependently (0.01–1 units/ml) and collagen (20 μg/ml) also enhanced the binding of platelets. Anti-LOX-1 antibody (10 μg/ml) significantly inhibited the enhanced binding of platelets to BLOX-1-CHO (P < 0.01). (D) PS liposome (0.1–10 μmol/liter) competitively inhibited the binding to BLOX-1-CHO of platelets, which are preactivated by thrombin (1 unit/ml). Data represent the means ± SEM of triplicate experiments. PC, phosphatidylcholine.