Table 3.
Comparison of contact pair prediction accuracy with CMA methods using observed information and contact definitions in HelixCorr
| Methods | Contact pair prediction |
δ-analysis (|δ| = 4) |
|
|---|---|---|---|
| Accuracy (%) | P-value | Accuracy (%) | |
| TMhit | 31.0 (±7.0) | 2.2e-109 | 56.8(±7.5) |
| TMhitL2 only | 23.6 (±7.5) | 3.2e-71 | 48.6(±8.0) |
| McBASC McLachlan | 10.0 | 6.5e-17 | 46.0 |
| OMES KASS | 9.0 | 1.2e-14 | 50.0 |
| ELSC | 10.0 | 6.5e-17 | 41.0 |
| CONSENSUS-14 | 12.0 | 1.4e-53 | 55.0 |
| CONSENSUS-R-5 | 11.0 | 3.6e-42 | 56.0 |
The standard error (SEboot) estimated by bootstrapping follows the ‘±’ sign.