Table 2.
Prevalence-Free Classification Accuracy Statistics for NAB List Learning Variables at Optimal Cutoff Scores
| Variable | Optimal Cutoff | Sensitivity (95% CI) | Specificity (95% CI) | PLR | NLR |
|---|---|---|---|---|---|
| All Impaired (aMCI and AD) vs. Control | |||||
| List A Immediate Recall | T≤44 | .78 (.65 - .88) | .80 (.70 - .87) | 3.83 | 0.27 |
| List B Immediate Recall | T≤44 | .66 (.51 - .78) | .79 (.69 - .86) | 3.05 | 0.44 |
| List A Short Delay Recall | T≤38 | .75 (.61 - .85) | .97 (.91 - .99) | 24.35 | 0.26 |
| List A Long Delay Recall | T≤40 | .76 (.63 - .87) | .97 (.91 - .99) | 24.95 | 0.24 |
| aMCI vs. Control | |||||
| List A Immediate Recall | T≤46 | .76 (.57 - .90) | .69 (.59 - .78) | 2.48 | 0.35 |
| List B Immediate Recall | T≤47 | .69 (.49 - .85) | .62 (.52 - .72) | 1.83 | 0.50 |
| List A Short Delay Recall | T≤48 | .86 (.68 - .96) | .72 (.63 - .81) | 3.13 | 0.19 |
| List A Long Delay Recall | T≤40 | .62 (.42 - .79) | .97 (.91 - .99) | 20.28 | 0.39 |
| AD vs. Control | |||||
| List A Immediate Recall | T≤40 | .85 (.65 - .96) | .90 (.82 - .95) | 8.29 | 0.17 |
| List B Immediate Recall | T≤44 | .85 (.65 - .96) | .79 (.69 - .86) | 3.95 | 0.20 |
| List A Short Delay Recall | T≤37 | .92 (.75 - .99) | .97 (.91 - .99) | 30.15 | 0.08 |
| List A Long Delay Recall | T≤40 | .92 (.75 - .99) | .97 (.91 - .99) | 30.15 | 0.08 |
| AD vs. aMCI | |||||
| List A Immediate Recall | T≤30 | .58 (.37 - .77) | .86 (.68 - .96) | 4.18 | 0.49 |
| List B Immediate Recall | T≤41 | .65 (.44 - .83) | .72 (.53 - .87) | 2.37 | 0.48 |
| List A Short Delay Recall | T≤30 | .73 (.52 - .88) | .83 (.64 - .94) | 4.24 | 0.33 |
| List A Long Delay Recall | T≤36 | .89 (.70 - .98) | .52 (.33 - .71) | 1.83 | 0.22 |
Note. PLR = Positive Likelihood Ratio; NLR = Negative Likelihood Ratio; aMCI = Amnestic mild cognitive impairment; AD = Alzheimer’s disease.