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. Author manuscript; available in PMC: 2009 Apr 10.
Published in final edited form as: Front Biosci (Landmark Ed). 2009 Jan 1;14:19–44. doi: 10.2741/3229

Figure 2. Effect of hepatic AMPKα2-CA expression on glycolytic and lipogenic gene expression in the liver of 6hours fasted ob/ob mice.

Figure 2

Adenovirus expressing AMPKα2-CA (Ad α2-CA) or β-gal (Ad β-gal) were injected in ob/ob and control mice and gene expression was analyzed 48 hours post-injection. Each value indicates the amount of mRNA with respect to that in 6 hours fasted control C57Bl6J mice, arbitrarily defined as 1. Fold increase is indicated below each graph column. *P < 0.05, **P < 0.01, #P < 0.005, ##P < 0.001 vs. control mice and $P < 0.05, §P < 0.005, §§P < 0.001 vs. ob/ob Ad β-gal-injected mice. L-PK, L-pyruvate kinase; GK, glucokinase; S14, Spot 14 ; SREBP-1, sterol regulatory element– binding protein-1; ChREBP, carbohydrate response element–binding protein; ACC, acetyl CoA-carboxylase; FAS, fatty acid synthase; SCD-1, stearoyl-CoA desaturase-1; GPAT, glycerol-3-phosphate acyltransferase.