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. Author manuscript; available in PMC: 2009 Apr 10.
Published in final edited form as: Front Biosci (Landmark Ed). 2009 Jan 1;14:19–44. doi: 10.2741/3229

Figure 4. Role of AMPKα2 in skeletal muscle mitochondrial function.

Figure 4

Substrate utilization by mitochondria were determined in permeabilized fibers of soleus (A) and plantaris (B) muscles of sedentary (SED) and active (ACT) AMPK 2 −/− (KO) mice and littermate (CT) controls. Respiration rates were measured during the cumulative addition of substrates in saponin-skinned cardiac fibers of control and AMPKα2−/− mice. VO2: rate of O2 consumption in μmol·min−1·g dw−1. G3P: glycerol-3-phosphate, Mal: malate, Oct: octanoylcarnitine, Pyr: pyruvate, Glu: glutamate. * p<0.05 vs. control mice.