. 2009 Mar 19;106(14):5587–5592. doi: 10.1073/pnas.0811968106

Table 1.

Substrates of wild-type and unlocked granzyme C

P5–P1↓P1′–P5′	Signal ratio (wild-type:unlocked)	Protein description	Accession
IIVYL₍₃₃₎↓YTKKV	0.086	60S ribosomal protein L34	Q9D1R9
EEGYN₍₂₁₃₎↓DGEVD	0.085	Acidic leucine-rich nuclear phosphoprotein 32 A	O35381
LVKFM₍₃₀₈₎↓CGEKQ	0.067	Flap endonuclease 1	P39749
LEAFM₍₁₂₀₎↓AEVED	0.053	ATP-dependent RNA helicase DDX42	Q810A7
NILMF₍₈₉₁₎↓TGETE	0.049	CTR9 homolog	Q62018
PNTSF₍₄₈₀₎↓ASDGS	0.046	5′–3′ exoribonuclease 2	Q9DBR1
PLEAF₍₁₁₉₎↓MAEVE	0.026	ATP-dependent RNA helicase DDX42	Q810A7
ALGFY₍₂₂₅₎↓DTSEE	Unlocked only	Cell division cycle 5-related	Q6A068
RLMEL₍₆₀₃₎↓SATVE	Unlocked only	170-kDa Centrosomal protein	Q6A065
PGIFY₍₁₁₎↓SDSFG	Unlocked only	MCM5	P49718
RACEM₍₇₃₎NGEEC	Unlocked only	DNA-binding protein Ikaros	Q03267
KVTFF₍₂₉₆₎↓EPSPG	Unlocked only	Staufen homolog 1	Q9Z108
KFDFM₍₁₀₎↓ASGED	Unlocked only	GRB2-related adaptor protein 2	O89100
EKCDY₍₆₀₂₎↓MDEVT	Unlocked only	hnRNP U-like protein 2	Q00PI9
AYIEF₍₄₃₈₎↓KSEAD	Unlocked only	Nucleolin	P09405
KPQVM₍₅₀₈₎↓AGTVK	Unlocked only	Pescadillo homolog 1	Q9EQ61
KLDFL₍₂₁₃₎↓EGDQK	Unlocked only	EBP2	Q9D903
PSSVF₍₁₁₃₎↓ASEFE	Unlocked only	LTV1 homolog	Q6NSQ7
LVAAY₍₆₂₀₎↓SGDSD	Unlocked only	RNA-binding protein 5	Q91YE7