Table 4.

Comparison of antiviral potency of C34-Chol versus C34, T20, and the second-generation inhibitor T1249

HIV isolate	IC90 viral infectivity, nM
	Experiment 1		Experiment 2
	C34-Chol	C34	C34-Chol	T20	T1249
DJ258	0.20	4.8	0.015	7.6	4.5
JRFL	0.16	20.0	0.36	20	8.3
NL4-3	0.16	5.4	0.09	6.1	2.6
CC 7/86	1.0	22.0	0.08	32	24
94ZW103	0.41	5.3	0.10	11	1.9
UG270	1.50	51.0	0.38	53	5.2
CM235	1.80	20.0	0.46	61	11
BZ162	0.37	6.1	0.10	9.2	2.2