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. Author manuscript; available in PMC: 2010 Feb 27.
Published in final edited form as: Adv Drug Deliv Rev. 2008 Dec 13;61(2):158–171. doi: 10.1016/j.addr.2008.11.002

Table 2.

Clearance time and rate for various types of normal human mucus.

Type of Mucus Clearance Time (min) Clearance Rate (mm/min) Ref.
Respiratory
 General 10–20 * [32]
 Maxillary Sinus 20–30 * [32]
 Nasal 8.8 * [213]
* 5–11 [80]
20 5 [79, 214, 215]
 Tracheal * 4.1±1.9 [216]
* 4.7 (range: 3.5–6) [216222]
* 15.5 (range: 4.5–30)# [223230]
 Bronchial * 2.4±0.5 [217]
 Small Airways * 1 [231]
Ocular 5–7.7 * [56]
*

Not determined.

#

Clearance rates were measured using a bronchoscopic or roentgenographic method, which generally results in higher measured rates of clearance, most likely due to the invasiveness of the procedures [229, 230].