Table 3.
Adverse events leading to discontinuation
| CoPAT (n = 8)a | IPAT (n = 25)a | |
|---|---|---|
| Anaphylactic reaction | 0 | 1 |
| Skinb | 4 | 4 |
| Red man syndrome | 0 | 1 |
| Diabetic gastroparesis | 1 | 0 |
| Vomiting not otherwise specified | 0 | 1 |
| Blood creatine phosphokinase increased | 1 | 2 |
| Cardiovascularc | 0 | 4 |
| Hypoxia | 0 | 1 |
| Infectiond | 0 | 3 |
| Fever | 0 | 2 |
| Renal failure | 2 | 3 |
| Sepsis | 0 | 2 |
| Thrombocytopenia | 0 | 1 |
aNumber of discontinuations due to an adverse event.
bSkin includes dermatitis bullous, dermatitis medicamentosa, erythematous rash, vesicular rash and rash not otherwise specified.
cCardiovascular includes cardiac arrest (two patients), cerebrovascular accident and circulatory collapse.
dInfection includes osteomyelitis not otherwise specified, staphylococcal pneumonia and staphylococcal bacteraemia.