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Histographs of SNpc DA neuronal survival following estrogen, IGF-1, PD98059 (MAPK/ERK inhibitor) and LY294002 (PI3K/Akt inhibitor) treatment. Timeline of treatments in Fig. 1(A). Values are mean percentage ± S.E.M of SNpc DA neuronal survival (lesion) ipsilateral vs. (control) contralateral intact side. Each value is calculated from 5 to 7 animals. * p < 0.05 compared to lesion, one-way ANOVA, Student Newman-Keuls posthoc.
