Table 2.
Risk of bias and funding source
| Random sequence generation | Concealment of randomisation | Blinding | Loss to follow up/drop out | Method of data analysis | Jadad score (/5) | Funding | |
| DeJongste 1994 | Not stated | Independent telephone service | Open label | 8% | Not stated | 2 | Government |
| DiPede 2001 | Not stated | Not stated | Blinded ECG assessment | 0% | Not stated | 3 | Not stated |
| ESBY 1998 | Not stated | Not stated | Open label | 7%* | Intention to treat | 2 | Government |
| Hauvast 1998 | Not stated | Not stated | Open label | 0% | Not stated | 2 | Government |
| Jessurum 1999 | Not stated | Not stated | Open label | 0% | Not stated | 2 | Industry |
| SPiRiT 2006 | Computer-generated | Independent R&D department | Open label | 9% | Intention to treat | 4 | Industry |
| Eddicks 2007 | Not stated | Not stated | Double blind | 0% | Not stated | 4 | Industry |
*: at 6-months follow up