Table 3.
Comparison of distributive frequencies of MRP1/ABCC1 Cys43Ser, Thr73lle, Arg723Gln, and Arg1058Gln polymorphisms in different ethnic populations.
| SNPs (Nucleic acid substitution) | Allelic frequency |
Population | References | NCBI SNP ID | |
|---|---|---|---|---|---|
| m | w | ||||
| Cys43Ser (128G>C) | 0.010(1/96) | 0.990(95/96) | Japanese | [16] | rs41395947 |
| 0(0/26) | 1(26/26) | Japanese | [14] | ||
| 0.005(2/416) | 0.995(414/416) | Chinese | This study | ||
| Thr73Ile (218C>T) | 0.010(1/96) | 0.990(95/96) | Japanese | [16] | rs41494447 |
| 0(0/26) | 1(26/26) | Japanese | [14] | ||
| 0.037(2/54) | 0.963(52/54) | Chinese | [17] | ||
| 0.014(1/72) | 0.986(71/72) | Chinese | [15] | ||
| 0.029(2/70) | 0.971(68/70) | Malay | [15] | ||
| 0(0/70) | 1(70/70) | Indian | [15] | ||
| 0(0/72) | 1(72/72) | Caucasian | [15] | ||
| 0.014(6/416) | 0.986(410/416) | Chinese | This study | ||
| Arg723Gln (2168G>A) | 0.073(7/96) | 0.927(89/96) | Japanese | [16] | rs4148356 |
| 0.038(1/26) | 0.962(25/26) | Japanese | [14] | ||
| 0.056(3/54) | 0.944(51/54) | Chinese | [17] | ||
| 0(0/72) | 1(72/72) | Chinese | [15] | ||
| 0.029(2/70) | 0.971(68/70) | Malay | [15] | ||
| 0(0/70) | 1(70/70) | Indian | [15] | ||
| 0(0/72) | 1(72/72) | Caucasian | [15] | ||
| 0.058(24/416) | 0.942(392/416) | Chinese* | This study | ||
| Arg1058Gln (3173G>A) | 0.010(1/96) | 0.990(95/96) | Japanese | [16] | rs41410450 |
| 0(0/26) | 1(26/26) | Japanese | [14] | ||
| 0.005(2/416) | 0.995(414/416) | Chinese | This study | ||
*
P<0.05 compared with Caucasian population