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. 2009 Apr 17;4(4):e5277. doi: 10.1371/journal.pone.0005277

Table 2. Comparison of saliva and PBMC human herpes virus DNA PCR results between groups of HIV-infected, antiretroviral suppressed patients with high CD8+/CD38+% and low absolute CD4+ T cell counts versus those with low CD8+/CD38+% and high absolute CD4+ T cell counts.

High CD8+/CD38+%- Low CD8+/CD38+%- P value
Low Abs. CD4+ count High Abs. CD4+ count
CMV DNA PCR
Positive saliva samples 10/35 5/20 0.77
Positive PBMC samples 8/40 3/20 0.61
Pts with ≥1 positive saliva 5/11 4/5 0.31
Pts with ≥2 positive saliva 4/11 1/5 1.00
Pts with all positive saliva 0/11 0/5 -
Mean within-subject mean saliva CMV DNA copy number (log10 copies/mL) 1.89 1.91 0.73
EBV DNA PCR
Positive saliva samples 25/35 15/20 0.83
Pts with ≥1 positive saliva 10/11 5/5 1.00
Pts with ≥2 positive saliva 8/11 4/5 1.00
Pts with all positive saliva 5/11 2/5 0.55
Mean within-subject mean saliva EBV DNA copy number (log10 copies/mL) 3.16 3.38 0.74
KSHV DNA PCR
Positive saliva samples 9/35 4/20 0.61
Pts with ≥1 positive saliva 7/11 3/5 1.00
Pts with ≥2 positive saliva 2/11 1/5 1.00
Pts with all positive saliva 0/11 0/5 -
Mean within-subject mean saliva KSHV DNA copy number (log10 copies/mL) 2.0 2.1 0.55