Quantification of ΔFosB induction in striatal regions after chronic morphine, Δ9-THC, ethanol, and cocaine treatments. The bar graphs show the mean number of ΔFosB+ cells in control animals and in animals subjected to chronic morphine, Δ9-THC, ethanol, or cocaine treatments in the core and shell subregions of the nucleus accumbens (NAc) and in the dorsal striatum (caudate-putamen, CPu). Data are expressed as mean ± SEM (n = 6–10 animals in each group). *P < 0.05 by t-test.