Table 5.
Summary of results for Hermann et al. (1984) and for meta-analysis of eight anti-D immunoglobulin studies, before and after adjusting for biases: estimated odds ratio of sensitization, comparing routine anti-D immunoglobulin against control, and corresponding ‘effective number of events’ in each arm†
| Bias adjustment |
Results for Hermann et al. (1984) analysis |
Results for meta-analysis |
|||||
|---|---|---|---|---|---|---|---|
| Odds ratio (95% CI) |
Effective number of events |
Odds ratio (95% CI) |
Effective number of events |
 |
|||
| Treated | Control | Treated | Control | ||||
| None | 0.24 (0.05, 1.10) | 2.1 | 8.5 | 0.28 (0.17, 0.46) | 19.7 | 70.8 | 0.05 |
| Additive biases | 0.39 (0.05, 3.04) | 1.3 | 3.3 | 0.29 (0.14, 0.57) | 10.4 | 36.1 | 00 |
| All biases | 0.37 (0.03, 4.68) | 0.8 | 2.2 | 0.25 (0.11, 0.56) | 7.0 | 28.5 | 00 |
†
Details are given in Section 5.2.