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. Author manuscript; available in PMC: 2009 Apr 9.
Published in final edited form as: J Comp Neurol. 2006 Oct 20;498(6):796–809. doi: 10.1002/cne.21087

Fig. 8.

Fig. 8

Diagrams for the possible regulatory pathway for PKs. A: Possible regulatory pathway for PK2 in circadian behavior. The receptors for PK2 are expressed in primary output targets of the suprachiasmatic nucleus (SCN). The projections from LHb-pineal gland or DMH-LC are possible pathways through which PK2 may regulate sleep/wake and arousal. B: Possible regulatory pathway of PK1 in autonomic function. PK1 mRNA is highly expressed in the nucleus tractus solitarius (NTS). The receptors for PK1 are localized in both ascending and descending pathways of the NTS. Shading represents areas where PK2 is expressed, and circled white areas represent areas where PKRs are expressed. Areas that are both shaded and circled represent areas where both PK2 and PKRs are expressed. Black arrows indicate direct projections, and gray arrows represent indirect projections.