Table 5.
Selectivity profile
| compound | p38α, IC50 (μM) | Akt1, IC50 (μM) | Furin, IC50 (μM) | LF, IC50 (μM) |
|---|---|---|---|---|
| 3j | >100 μM | 20% at 100 μM | > 50 μM | >100 μM |
| 7b | >100 μM | 14% at 100 μM | > 50 μM | >100 μM |
| 8f | >100 μM | 27% at 100 μM | > 50 μM | >100 μM |
| 9 | >100 μM | 11% at 100 μM | > 50 μM | >100 μM |